Thursday, August 1, 2013

New screens, more horsepower may be part of Kindle Fire fall update

Amazon

12 hours ago

fire HD

Amazon

The current Kindle Fire HD with an 8.9-inch screen may get a new screen and upgraded internals.

Amazon's popular Kindle Fire tablets are slated for a major update this fall, according to the blog BGR's anonymous sources. New screens, better build quality, and an internal overhaul should bring the devices more in line with the latest from Google and Apple.

The most visible change will be to the screen. The 7-inch Kindle Fire HD will be getting a 1920x1200 resolution, the same as Google's new Nexus 7, and the 8.9-inch device will get a 2560x1600 one, the same as the Nexus 10. But because the screen is smaller, those pixels are packed in even tighter, which would make the Kindle's screen among the sharpest on the market.

BGR's source also said there will be an angular new look to the Kindle and redesigned button layout. The Kindle Fire line has always been a bit vanilla, so this may help woo people attracted to the more radical designs of Sony and Barnes & Noble's tablets.

Lastly, the internals are getting a big boost: a new quad-core Snapdragon chip, 2 GB of RAM (twice the amount in current models), and presumably a few more under-the-hood boosts. Amazon declined to comment to NBC News about the proposed changes.

If it sounds a bit strange that the device could be more powerful than an iPad at half the price, that's because Amazon is okay with taking a financial hit on the device in order to expand its empire into your living room, according to IHS analyst Rhoda Alexander.

"Amazon?s initial tablet offering was a loss leader at its debut, based upon the IHS teardown," wrote Alexander in an email to NBC News. "While Amazon does strive for long-term profitability they have demonstrated willingness to accept short-term losses in key markets as part of their overall strategy."

That said, it's not always the bigger screen or faster processor that wins in the end, Alexander cautioned. "The history of the tablet market to date shows that success is not as simple as winning on specifications."

No word on what might happen to the low-cost, non-HD Kindle Fire, but Amazon's habit in the past has been to keep such models around for a surprisingly long time, albeit not actively promoted.

With Apple rumored to be delaying its major iPad updates, and very little in the way of competition in the Android tablet world apart from Google and Samsung's latest, the new Amazon tablets could make quite a splash. If the launch timing reported is correct, we'll know for sure later in the year.

Devin Coldewey is a contributing writer for NBC News Digital. His personal website is coldewey.cc.

Source: http://feeds.nbcnews.com/c/35002/f/663301/s/2f5c1de0/sc/15/l/0L0Snbcnews0N0Ctechnology0Cnew0Escreens0Emore0Ehorsepower0Emay0Ebe0Epart0Ekindle0Efire0Efall0E6C10A798150A/story01.htm

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Tom Brady, Peyton Manning win secret golf match on Hail Mary

Tom Brady, Peyton Manning win secret golf match on Hail Mary - CBSSports.com

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Source: http://feedproxy.google.com/~r/cbssportsline/nfl_news/~3/JHXHdftks6Y/tom-brady-peyton-manning-win-secret-golf-match-on-hail-mary

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Wednesday, July 31, 2013

The Life Extension Blog: Red Clover Kills Prostate Cancer Cells

By Michael A. Smith, MD

More than 238,000 men will be diagnosed with prostate cancer in the United States, and nearly 30,000 will die from it.1

In fact, about one in six men will be diagnosed with this condition during their lifetime.

And these epidemic statistics don?t even include the disabilities and deaths that occur in response to prostate cancer treatment.

So it?s always nice to see research results that point to a potential cancer killer like red clover. Let?s take a look at the study.

Red Clover?s Anti-Cancer Effects

Red clover contains a weak phytoestrogen called formononetin. Now before going any further, I know that some of you object to using a phytoestrogen for prostate cancer.

Please keep in mind that clinical studies have shown that some phytoestrogens have anti-cancer properties.2,3 And the present study we?re talking about today supports the same conclusion.

In the study, researchers investigated the anti-cancer mechanisms involved in the effect of formononetin on prostate cancer cells. Their results suggest that higher concentrations of formononetin inhibited the proliferation of prostate cancer cells, by inactivating the enzymes responsible for cell growth, called signal-regulated kinase and mitogen-activated protein kinase.4

This inhibition of cell growth enzymes resulted in apoptosis (programed cell death) in prostate cancer cells. They concluded that red clover?s formononetin induces prostate cancer cell death ? at least in petri dishes.4

Considering that red clover plants were widely used clinically, the researchers also believed that their results provide a foundation for future development of different concentrations of red clover standardized to formononetin for treatment of prostate cancer.4

Other Phytoestrogens that Fight Against Prostate Cancer

Plant-derived compounds called isoflavones,which are abundant in soybeans, modulate estrogen signaling in the human body via interaction with estrogen receptors. Thus, these compounds are sometimes classified as ?phytoestrogens?.

Isoflavones have been investigated for their anti-cancer effects, but their ability to affect hormone-responsive tissues appears to influence the prostate. Evidence suggests that isoflavones decrease free serum testosterone levels and may inhibit testosterone-mediated prostate cell growth.5

These compounds were also shown to block the activity of 5?-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT), which promotes prostate growth.6

Supplementation with soy isoflavones has been found to reduce PSA levels in men with prostate cancer7, and a soy-based dietary supplement containing isoflavones, lycopene, silymarin, and antioxidants was shown to significantly delay PSA progression in patients who underwent curative treatment for prostate cancer8.

In addition to preventing prostate cell proliferation, isoflavones may increase programmed cell death (i.e., apoptosis) in low-to-moderate grade tumors from prostate cancer patients.

Of Course, Prevention is Always Better

No single cause of prostate cancer has ever been determined, but the single biggest risk factor for prostate cancer is eating products that contain animal fat. In an old well-designed study involving over 6,000 men, those who routinely ate milk, cheese, eggs and meat had a 3.6 times greater risk of fatal prostate cancer than those who did not.9

A more recent case-control study published on the National Cancer Institute?s website shows a higher risk of prostate cancer with increased intake of total calories, red meat, and animal fat and protein. Yet a higher consumption of allium vegetables, peppers, and mushrooms are associated with reduced risk.10

And lastly, a study designed to examine fat intake in relation to lethal prostate cancer and all-cause mortality was published this month in the Journal of the American Medical Association.

The results showed that among men with non-metastatic prostate cancer (cancer that is contained within the prostate gland), replacing carbohydrates and animal fat with vegetable fat reduces the risk of all-cause mortality.

The authors concluded that the potential benefit of vegetable fat for prostate cancer-specific outcomes merits further research.11

So what does this mean? Pretty simple. Eat less animal fat and more vegetables! Something all of us inherently know we should be doing.

References:

  1. Available at: http://www.cancer.org/cancer/prostatecancer/detailedguide/prostate-cancer-key-statistics.
  2. Anticancer Res. 2013 Jan;33(1):39-44.
  3. Maturitas. 2013 Jun;75(2):125-30. doi: 10.1016/j.maturitas.2013.03.006. Epub 2013 Apr 6.
  4. Horm Metab Res. 2012 Apr;44(4):263-7.
  5. Prostate. 2004 May 1;59(2):141-7.
  6. J Endocrinol. 1995 Nov;147(2):295-302.
  7. J AOAC Int. 2006 Jul-Aug;89(4):1121-34.
  8. Eur Urol. 2005 Dec;48(6):922-30.
  9. Am J Epidemiol. 1984 Aug;120(2):244-50.
  10. National Cancer Institute. http://dceg.cancer.gov/research/cancer-types/prostate/shanghai-case-control-study-prostate-cancer. Accessed 6/28/2013.
  11. JAMA Intern Med. 2013 Jun;10:1-8.

Source: http://blog.lef.org/2013/07/red-clover-kills-prostate-cancer-cells.html

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Monday, July 29, 2013

Dr. Pecco is a mentally unstable dentist from Rome who gained...

Dr. Pecco is a mentally unstable dentist from Rome who gained notoriety when some of his patients went missing. He was investigated but never charged. In his spare time he hunts great white sharks in the Mediterranean Sea, drives his Countach really fast, and makes awesome synth music.

Source: http://2087.tumblr.com/post/56668577496

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Energy Watchdog 'Failing Consumers', Say MPs

By Tadhg Enright, Business Reporter

The energy watchdog, Ofgem, is failing consumers and undermining trust in the market, a group of MPs have said - urging it to "use its teeth a bit more".

A report by the Energy and Climate Change Select Committee has said there is a "lack of transparency" about profits made by the Big Six energy providers.

Committee member and Lib Dem MP Sir Robert Smith said: "At a time when many people are struggling with the rising costs of energy, consumers need reassurance that the profits being made by the Big Six are not excessive.

"Unfortunately, the complex vertically integrated structure of these companies means that working out exactly how their profits are made requires forensic accountants."

Labour MP John Robertson added: "Ofgem needs to use its teeth a bit more and force the energy companies to do everything they can to prove that they are squeaky clean when it comes to making and reporting their profits."

There has been long standing criticism of the UK energy market in which six major competitors show little evidence of competing with each other on price.

Rising prices for consumers in recent years has been blamed on higher wholesale prices for energy providers however the Committee notes in its report that many of Britain's major providers are generators of energy and therefore profit from higher wholesale prices too.

The Big Six have also been criticised for offering a confusing range of tariffs which give the impression of greater consumer choice but offer little in the way of discounts.

British Gas and EDF customer Mary Phillips told Sky News that in the winter she frequently has to choose between spending on food or fuel, and that competition in the energy market has done nothing to help.

She said: "I keep getting notes from all these different energy companies saying that they're making their bills much easier to understand. You're joking!

"Every single different supplier says that they're going to give me a much better deal than all the other suppliers. I don't believe it really. I think they might do it for about three months and then it will all go up suddenly."

As the industry's watchdog, Ofgem has the power to order an inquiry into competition in the energy market but has chosen not to do so.? Instead it hopes that the threat of such a forensic analysis of the Big Six's energy practices will encourage them to clean up their acts.

Ofgem's Rachel Fletcher said: "We share the committee's goal of restoring consumers' trust.

"We agree with the committee that suppliers have been poor at communicating with their customers.

"Ofgem has made energy companies produce yearly financial statements, which have been reviewed twice by independent accountants and found to be fit for purpose."

The report also criticises the Government for not doing enough to help millions of low-income families living in poorly insulated homes and who struggle with fuel poverty.

The MPs argue that programmes to help protect the most vulnerable should be funded through direct taxation rather than levies on the bills of those who can afford it.

Sir Robert said: "Fuel poverty is getting worse as energy prices rise making it all the more critical that the Government must respond to the Hills Review as a matter of urgency.

"Tax-funded public spending is a less regressive mechanism than levies on energy bills, which can hit some of the poorest hardest. Shifting the emphasis from levies to taxation would help protect vulnerable households."

Source: http://news.sky.com/story/1121455

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